Protein Modification Reagents
TARGETMOL CHEMICALS INC CL-C6-PEG4-O-CH2COOH 50MG
Also available in 5 mg 10 mg 100 mg and bulk. Please contact Fisher for quotes. Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is an effective pegylated PROTAC linker which is often used in PROTAC synthesis of chloroanes (HaloPROTACs). purity: 99%
Medchemexpress LLC DBCO-PEG6-NHS ester | 95.0% | 737.79 g·mol⁻¹ | C38H47N3O12 | 10 MG
DBCO-PEG6-NHS ester is a bifunctional click-chemistry reagent combining a dibenzocyclooctyne (DBCO) moiety and an N-hydroxysuccinimide (NHS) ester separated by a six-unit polyethylene glycol spacer. It is designed for amine-specific conjugation and copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-functionalized partners, and is supplied as a light yellow liquid.
- Bifunctional linker with DBCO and NHS ester groups.
- PEG6 spacer improves solubility and reduces steric hindrance.
- Reacts with primary amines for stable covalent attachment.
- Performs copper-free SPAAC with azide groups for bioorthogonal labeling.
- Purity approximately 95% as provided in product documentation.
- Store protected from light and under inert atmosphere; recommended low-temperature storage for long-term stability.
Medchemexpress LLC Dspe-peg-fitc | 1000788-53-3 | >=95.0% | 100 MG
DSPE-PEG-FITC (average MW 10,000) is a fluorescein-labeled PEGylated phospholipid that functions as a fluorescent lipid probe for incorporation into liposomes, micelles, and other lipid-based nanocarriers. Its amphiphilic structure allows integration into lipid bilayers to enable optical labeling, tracking, and imaging of nanoparticles in vitro and in vivo.
- Fluorescent label FITC for visualization and tracking.
- Average molecular weight 10,000 Da.
- Amphiphilic structure integrates into lipid bilayers.
- Suitable for liposome, micelle, and nanoparticle formulation.
- Available in multiple package sizes for experimental flexibility.
Medchemexpress LLC HY-103602A 100mg Medchemexpress, (S,R,S)-AHPC-PEG3-NH2 CAS:2010159-56-3 Purity:>98%
Medchemexpress, HY-103602A 100mg (S,R,S)-AHPC-PEG3-NH2 CAS:2010159-56-3 (S,R,S)-AHPC-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 1-(4-(1,2,4,5-tetrazin-3-yl)phenyl)-3,19-dioxo-6,9,12,15-tetraoxa-22,23-... | 95.0% | 723.82 | C30H41N7O10S2 | 5 MG
Tetrazine-PEG4-SS-NHS is a cleavable PEG4 linker that features a tetrazine reactive group, a disulfide (SS) cleavable spacer, and an N-hydroxysuccinimide (NHS) ester for efficient bioconjugation and click chemistry applications.
- Cleavable disulfide spacer enables reductive release of payloads.
- Tetrazine group allows inverse electron demand Diels-Alder (iEDDA) click reactions.
- N-hydroxysuccinimide (NHS) ester provides amine-targeted conjugation chemistry.
- PEG4 spacer improves solubility and provides flexibility between conjugated partners.
- Typical purity 95.0% by NMR.
- Molecular weight 723.82, solid, purple to purplish red in color.
- Storage: powder at -20 °C; in solvent store at -80 °C (up to 6 months) or -20 °C (up to 1 month).
Molecular Dimensions 50% V/V PEG SMEAR HIGH (250ML)
PEG is an effective crystallization agent due to its protein-protein interaction promoting properties. The BCS Screen overcomes the impracticality of sampling all PEG varieties that has led to a few variants predominating in the most common screens. PEG Smears are designed primarily for efficient screening of chemical space. It is generally thought that well-defined, single PEG species produce the best diffracting crystals. Thus, optimization might involve identifying the single PEG compound that produces the best crystal for structural studies. MOLECULAR DIMENSIONS INC mfg# MD2-250-260
Broadpharm Iodoacetamido-PEG6-azide| 100mg| 1240737-77-2| Purity 98%
Iodoacetamido-PEG6-azide| 100mg| 1240737-77-2| Purity 98%
Medchemexpress LLC DSPE-PEG-FITC | 1000788-53-3 | 95.0% | 100 MG
DSPE-PEG-FITC is a fluorescein (FITC)-labeled PEGylated phospholipid (average molecular weight 1000) supplied as a yellow powder for research applications. It is used to introduce a green fluorescent label into liposomes, micelles, and other lipid-based nanoparticles for visualization and tracking in biological studies.
- Fluorescent tag for green fluorescence detection (FITC).
- PEGylated phospholipid for stable incorporation into lipid bilayers and micelles.
- Average molecular weight 1000 to define PEG chain length.
- Reagent grade purity, 95%.
- Supplied as a yellow powder with defined cold-storage recommendations.
- Intended for research use only.
Medchemexpress LLC Dde Biotin-PEG4-DBCO | 1807512-43-1 | 96.17% | C47H61N5O9S | 100 MG
Dde Biotin-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. PROTACs consist of two different ligands connected by a linker; one for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a DBCO group
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that have azide groups
- Utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC Mal-amido-PEG8-NHS ester | 756525-93-6 | MFCD11041144 | 98.0% | 689.71 g/mol | C30H47N3O15 | 10 MG
Mal-amido-PEG8-NHS ester is a heterobifunctional polyethylene glycol linker used for bioconjugation and PROTac synthesis. It contains a maleimide group reactive with thiols and an N-hydroxysuccinimide (NHS) ester reactive with amines, separated by an eight-unit PEG spacer to improve aqueous solubility and conjugate flexibility. The product is a viscous, colorless to light-yellow liquid with high purity and defined storage conditions.
- Maleimide and NHS functional groups for thiol- and amine-specific coupling.
- Peg8 spacer enhances solubility and flexibility of conjugates.
- High purity suitable for research and conjugation workflows.
- Soluble in DMSO (≥100 mg/mL) and compatible with common in vivo formulations.
- Stable when stored frozen in pure form (-20°C recommended).
Cayman Chemical BIotIn-PEG4-NHS 50mg
An amine reactive reagent; has been used in the biotinylation of proteins and antibodies
Cayman Chemical -BIotIn-PEG3-amIn 250mg
A synthetic intermediate; has been used in the synthesis of biotinylated siderophores for whole-cell bacterial pull-down assays, as well as in the synthesis of protein-polysaccharide conjugate vaccines for S. pneumoniae
eMolecules 14-(Amide-PEG4-ethylcarbamoyl)tridecanoic t-butyl ester | Broadpharm |532.763 | C28H56N2O7 | 95.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCC(=O)NCCOCCOCCOCCOCCN | 100mg | 784455750
14-(Amide-PEG4-ethylcarbamoyl)tridecanoic t-butyl ester | Broadpharm |532.763 | C28H56N2O7 | 95.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCC(=O)NCCOCCOCCOCCOCCN | 100mg | 784455750
Medchemexpress LLC Dspe-peg-cooh | 98.1% | 5000 (Average) | 50 MG
DSPE-PEG-COOH (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. It can be used in drug delivery research.
- Improves delivery efficiency
- Enhances tissue specificity
- Suitable for drug delivery research
- PEG lipid